NICE Reveals Surprising Truth About Hormone Replacement Therapy

  • WorldScope
  • |
  • 07 November 2024
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Hormone Replacement Therapy: New Insights from NICE

Hormone replacement therapy (HRT) is a pivotal treatment for many women experiencing menopause symptoms. Recent guidance from the National Institute of Health and Care Excellence (NICE) provides clarity on HRT’s impact, indicating that it does not alter life expectancy for those undergoing treatment. This revelation stems from a meticulous review of data linking HRT with various health conditions, including heart disease, stroke, certain cancers, and dementia.

Understanding HRT and Its Benefits

HRT functions by replenishing hormones such as oestrogen and progestogen, which decline when a woman’s menstrual cycle ceases—typically between ages 45 and 55. The therapy is delivered through various forms, including gels, creams, tablets, and sprays.

NICE emphasizes the necessity for healthcare professionals to consider each woman’s unique circumstances when discussing treatment options. The updated guidance includes user-friendly illustrations to facilitate informed discussions between general practitioners and patients regarding potential health risks associated with HRT.

An independent expert panel reviewed the scientific evidence regarding HRT’s effects on health risks. Dr. Marie Anne Ledingham noted that women over 45 taking combined HRT did not experience a heightened risk of coronary heart disease or cancers compared to those who have never used HRT.

While the data suggests no significant increase in risks for major conditions like heart disease or osteoporosis—where HRT actually decreases fracture risk—there is a slight uptick in breast cancer risk associated with prolonged use of combined HRT. For example:

  • 59 in every 1,000 women who never use HRT may develop breast cancer.
  • This number increases to 79 in every 1,000 after five years of combined HRT usage.
  • After ten years, the figure rises to 92 in every 1,000.

Furthermore, starting HRT after age 65 may correlate with a modestly increased risk of developing dementia; however, younger women do not show this elevated risk.

The Path Forward for Menopausal Care

The NICE guidelines advocate for the integration of cognitive behavioral therapy (CBT) alongside HRT as a means to address menopause symptoms such as night sweats and sleep disruption. While prior drafts suggested CBT could replace HRT entirely—a proposal met with considerable criticism—the final guidance affirms HRT remains the primary treatment option.

Professor Jonathan Benger from NICE highlighted the growing awareness regarding menopause’s impact on women’s lives but noted that additional efforts are necessary to support women from diverse backgrounds who may lack access to effective treatments.

As awareness about menopause continues to evolve, it is crucial for healthcare systems to ensure that all women receive comprehensive support tailored to their individual needs. With increased understanding and improved access to treatment options like HRT, more women can navigate this challenging phase of life with confidence and assurance.

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